Research Links
Knowledge is the Anecdote to Misinformation
Until clinical trials are financially supported for arm's length, triple blind evidence, studies are essentially anecdotal. BUT that doesn't mean that putting High Phenolic (HP) EVOO to the test in your daily regimen won't have impact!
Below is a comprehensive list of studies - you can come to your own conclusions.
Articles detailing the debating on how to measure polyphenols in olive oil in order to comply with the health claim of a minimum 250mg per kg. written by Athan Gadanidis published on www.oliveoiltimes.com
http://www.oliveoiltimes.com/
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Clinical trials VIDEO Interview with Magiatis
https://youtu.be/EeCEMa41X5s
Research has indicated that oleocanthal, aside from its beneficial anti-inflammatory effects may also increase the efficacy of pharmaceuticals.
See https://medium.com/beyond-organic-beyond-extra-virgin/oleocanthal-rich-evoo-a-medical-food-83bcb2a5e262
A group of mothers with autistic children found that high phenonolic olive oil added to a nutrition protocol had additional benefits. See When a Child Stops Playing
https://aristoleo.com/when-a-child-stops-playing-autism-and-high-phenolic-olive-oil/
The Health Benefiting Mechanisms of Virgin Olive Oil Phenolic Compounds
https://www.mdpi.com/1420-3049/21/12/1734/htm
Virgin Olive Oil and Health: Summary of the III International Conference on Virgin Olive Oil and Health Consensus Report, JAEN (Spain) 2018.- The type of olive oil should be considered when providing recommendations to the population because additional benefits can be conferred when the phenolic content of olive oil is high.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770785/
The multifunctional therapeutic potentiality of extra virgin olive oil administration through the intervention in pathophysiological mechanisms: Focus on Alzheimer’s disease
https://gsconlinepress.com/journals/gscarr/sites/default/files/GSCARR-2021-0081.pdf
Oleocanthal; kills cancer cells.
https://www.oliveoiltimes.com/health-news/extra-virgin-olive-oil-oleocanthal-kills-cancer-cells/46659
Key Mechanism Links Olive Oil to Protection Against Breast Cancer
https://www.oliveoiltimes.com/health-news/breast-cancer-and-olive-oil/3891
Oleocanthal, a Polyphenol in Olive Oil, Positively Impacts Human Melanoma Cells
https://www.oliveoiltimes.com/health-news/olive-oil-polyphenol-positively-impacts-human-melanoma-cells/52838
Phenols in Extra Virgin Olive Oil Inhibit Colon Cancer Cell Growth
https://www.oliveoiltimes.com/health-news/extra-virgin-olive-oil-phenols-inhibit-colon-cancer-cell-growth/44705
Mycobacteria emulsified in olive oil-in-water trigger a robust immune response in bladder cancer treatment
https://www.nature.com/articles/srep27232#t1
Antitumor Action
- Component in EVOO Kills Cancer Cells
- Olive Oil May Help Prevent and Treat Brain Cancer, Study Shows
- Key Mechanism Links Olive Oil to Protection Against Breast Cancer (Consider also:Beyond Wearing Pink: How You Can Support Breast Cancer Awareness)
- Phenols in Extra Virgin Olive Oil Inhibit Colon Cancer Cell Growth
- Olive Oil Found to Help Prevent Skin Cancer
- Researchers Link Oleocanthal to Cancer
- Olive oil intake is inversely related to cancer prevalence: a systematic review and a meta-analysis of 13800 patients and 23340 controls in 19 observational studies
- Oleocanthal, a Polyphenol in Olive Oil, Positively Impacts Human Melanoma Cells
- Olive Oil Found to Help Prevent Skin Cancer
- How EVOO Helps Prevent Colon Cancer
- Phenols in Extra Virgin Olive Oil Inhibit Colon Cancer Cell Growth
- Olive Oil Offers Promising Role in Treatment of Bladder Cancer
- Olive Oil May Be Useful in Brain Cancer Chemoprevention
- Researchers Link Oleocanthal to Cancer, Alzheimer’s Prevention
Cardioprotective action, LDL, HDL, atherosclerotic plaque, hypotension, strokes
- Olive oil as medicine: the effect on blood lipids and lipoproteins-University Davis California
- Olive oil as medicine: the effect on blood pressure-University Davis California
- Olive Oil Seen as a Treatment for Heart Failure
- Exclusive Olive Oil Consumption Protects Against Coronary Artery Disease
- Olive Oil Improves Blood Lipid Profile, Reduces Risk of Heart Disease
- Olive Oil Improves Heart Health
- Olive Oil Polyphenols Reduce Bad Cholesterol and Plaque Formation
- Study Finds Olive Oil Can Be Better than Medication for Heart Disease
- EVOO Effective in Lowering High Blood Pressure
- Plenty of Olive Oil Might Help Prevent Strokes, Researchers Find
- Adding 2 Tablespoons of Olive Oil Can Improve Blood Vessel Function
- Two Tablespoons of High Quality Olive Oil Every Day Help Protect the Heart
- Breakfast with High-Phenol EVOO Reduces Inflammation Linked to Diabetes, Heart Disease
- More Evidence Olive Oil is Good for the Heart
- The Benefits Of Olive Oil For Cholesterol Patients
- Olive Oil and Interventional Cardiology
- Anti-inflammatory effect of virgin olive oil in stable coronary disease patients: a randomized, crossover, controlled trial
Diabetes – Blood sugar control
- Long-Term Olive Oil Consumption Lowers Risk of Diabetes
- Extra Virgin Olive Oil Reduces Postprandial Glucose After High GI Meal in Type 1 Diabetes
- Benefits of Olive Oil Consumption in Type 2 Diabetes Treatment
- Patent Applicant Claims Olive Polyphenols Help Blood Sugar Control
- Breakfast with High-Phenol EVOO Reduces Inflammation Linked to Diabetes, Heart Disease
- Mediterranean Diet with Extra Virgin Olive Oil May Protect from Diabetes
- Mediterranean Diet with Olive Oil Shown to Modulate Gut Bacteria, Improve Insulin Sensitivity and Metabolic Syndrome
- How to Manage Your Type 2 Diabetes with Diet
Digestive system
- Phenols in Extra Virgin Olive Oil Inhibit Colon Cancer Cell Growth
- Olive Oil For a Healthy Digestive System
- Olives a Potential Source of Probiotics
- Olive oil and the digestive system
- Extra Virgin Olive Oil a Potential Functional Food for Colitis
- New Potential Health Benefit Of Olive Oil For Peptic Ulcer Disease
Osteoporosis, bone mass and density, osteoarthritis, rheumatoid arthritis
- Olive Oil Joins the Fight Against Osteoporosis
- Olive Oil Phenols Help Protect Bone Mass
- Powerful Anti-Inflammatory Benefits of Olive Oil
Alzheimer’s, memory loss, neuroprotective action
- How Extra Virgin Olive Oil Can Protect from Alzheimer’s Disease
- Extra-Virgin Olive Oil Helps Preserve Memory and Protect Against Alzheimer’s Disease, Study Finds
- Extra Virgin Olive Oil Preserves Memory and Protects Brain Against Alzheimer’s Disease
- Extra Virgin Olive Oil May Prevent Alzheimer’s, Study Finds 2017
- Extra Virgin Olive Oil May Prevent Alzheimer’s Disease 2013
- Researchers Link Oleocanthal to Cancer, Alzheimer’s Prevention
- Researchers Explore Role of Olive Oil Phenols in Prevention of Neurodegenerative Diseases
Parkinson's
Antioxidant action
- Extra Virgin Olive Oil Can Reduce Oxidative Stress
- Role of Olive Oil in Reducing Oxidative Stress
- Polyphenols antioxidants in olive oil
- Extra Virgin Olive Oil Can Protect the liver from Oxidative Stress
Anti-inflammatory, antimicrobial, antibacterial action
- Ibuprofen-like activity in extra-virgin olive oil
- Oleocanthal: A Naturally Occurring Anti-Inflammatory Agent in Virgin Olive Oil
- Olive Oil and Infection
- Olive Oil Component Stops Gut Bacteria Linked To Heart and Brain Diseases
- Anti-inflammatory effect of virgin olive oil in stable coronary disease patients: a randomized, crossover, controlled trial
- How The Olive Compound Hydroxytyrosol Helps Stop Infections
- Antimicrobial, antioxidant and anti-inflammatory phenolic activities in extra virgin olive oil
- Powerful Anti-Inflammatory Benefits of Olive Oil
Genoprotective action
- Olive Oil May Affect How Genes Function
- ‘Omics’ Data Reveals Impact of Olive Oil on Human Gene Expression
- Olive Oil Benefits are in the Genes
Antidepressant action
Anti-aging action
Strengthening of the immune system
Others
- Topical Olive Oil Prevents Pressure Ulcers in Immobilized Patients
- Extra Virgin Olive Oil More Effective than Ibuprofen in Treating Menstrual Pain (dysmenorrhea)
- Olive Oil Beneficial During Fertility Treatment
- Olive Oil Works Wonders for Babies
- Mediterranean Diet, Heavy on the Olive Oil, Can Reduce Risk of Chronic Disease
- Olive Oil Shown to Protect and Promote Liver Health
- Olive Oil Protects Liver
- Diet could REVERSE negative effects of high-fat food – and CURE liver disease
- Important Minor Compounds in Olive Oil – Emanuel Hatzakis Penn State University
- Oleic acid content is responsible for the reduction in blood pressure induced by olive oil
- The FDA’s Take on the Benefits of Olive Oil
- New Phenolic Compounds Unveiled at Harvard Conference
- The Right Olive Oil ‘Dosage’ for Those at High Risk of Cardio Diseases
- Mediterranean diet pyramid today. Science and cultural updates
- Mediterranean Diet May Reduce Risk of Kidney Disease
- Mediterranean Diet, Heavy on the Olive Oil, Can Reduce Risk of Chronic Disease
- Frying Vegetables in Extra Virgin Olive Oil Recommended for Men With Prostate Cancer
- Use Olive Oil for Frying
- Greek olive oil and history
- 10 Ancient Uses of Olive Oil
- Summer Skin Care Tips with Olive Oil
- 10 extra virgin olive oil benefits you never knew
- Benefits of Olive Oil for Hair
- Olive oil helps to cure headaches
- Benefits of Olive Oil for Skin
- Biological action of A-Tocopherol